B03 – Controlling fluorescence emission of single molecules by vibrational excitation
Funding period: 01/2008 – 12/2019
Principal investigator: Andreas Zumbusch
Scientific staff: Gurthwin Bosman, Christoph Kölbl, Felix Noll, Patricia Scheel, Romedi Selm, Simon Wiktorowski, Martin Winterhalder
We study the fluorescence emission of single molecules after controlled excitation of their vibrational states. In our excitation scheme, fluorescence emission will be switched by vibrational excitation. Two implementations are used: i) Non-linear optical excitation of vibrational states and ii) direct infrared excitation of vibrations. Due to symmetry constraints, both schemes are complementary and address different vibrational states. In either case, time-resolved monitoring of ultrafast vibrational relaxation phenomena is possible. Both methods will be used to study local heterogeneities in thin polymer films on basis of single molecules.
For further information please also refer to the group website: AG Zumbusch.
List of publications
2018
- P. Fimpel, C. Riek, L. Ebner, A. Leitenstorfer, D. Brida, and A. Zumbusch
Boxcar detection for high-frequency modulation in stimulated Raman scattering microscopy
Appl. Phys. Lett. 112 161101 (2018) - DOI: 10.1063/1.5022266
2016
- C. Riek, C. Kocher, P. Zirak, C. Kölbl, P. Fimpel, A. Leitenstorfer, A. Zumbusch, D. Brida
Stimulated Raman scattering microscopy by nyquist modulation of a two-branch ultrafast fiber source
Opt. Lett. 41 3731 (2016) - DOI: 10.1364/OL.41.003731
2015
- S. Wiktorowski, E. Daltrozzo, A. Zumbusch
Water-soluble Pyrrolopyrrole Cyanine (PPCy) near-infrared fluorescent pH indicators for strong acidity
RSC Advances, 5 29420 (2015)
DOI: 10.1039/C5RA04812E
2014
- T. Marks, E. Daltrozzo, A. Zumbusch
Azacyanines of the Pyrrolopyrrole Series
Chem. Eur. J. 20, 6494 (2014) - DOI: 10.1002/chem.201304235 - S. Wiktorowski, C. Rosazza, M. J. Winterhalder, E. Daltrozzo, A. Zumbusch
Water-soluble Pyrrolopyrrole Cyanine (PPCy) NIR fluorophores
Chem. Comm. 50, 4755 (2014) - DOI: 10.1039/c4cc01014k
2012
- R. Selm, G. Krauss, A. Leitenstorfer, A. Zumbusch
Non-iterative characterization of few-cycle laser pulses using flat-top gates
Optics Express 20, 5955 (2012) - DOI: 10.1364/OE.20.005955 - S. Wiktorowski, G. M. Fischer, M. J. Winterhalder, E. Daltrozzo, and A. Zumbusch
Photophysics of aminophenyl substituted pyrrolopyrrole cyanines
Physical Chemistry Chemical Physics 14, 2921 (2012) - DOI: 10-1039/C2CP23330D
2011
- M. Winterhalder, A. Zumbusch, M. Lippitz, M. Orrit
Toward Far-Field Vibrational Spectroscopy of Single Molecules at Room Temperature
J. Phys. Chem. B 115, 5425 (2011) - G. M. Fischer, E. Daltrozzo, and A. Zumbusch
Selective NIR chromophores: Bis-Pyrrolopyrrole Cyanines
Angew. Chem. Int. Ed. 50, 1406 (2011) - W. Akers, C.-H. Kim, M. Berezin, K. Guo, Kevin, R. Fuhrhop, G. Lanza, G. Fischer, E. Daltrozzo, A. Zumbusch, X. Cai, L. Wang, S. Achilefu
Noninvasive Photoacoustic and Fluorescence Sentinel Lymph Node Identification using Dye-Loaded Perfluorocarbon Nanoparticles
ACS Nano 5, 173 (2011)
2010
- G. M. Fischer, C. Jüngst, M. Isomäki-Krondahl, D. Gauss, H. M. Möller, E. Daltrozzo, and A. Zumbusch
Asymmetric PPCys: Strongly fluorescing NIR labels
Chem. Commun. 46, 5289 (2010)
2009
- M.Y. Berezin, W.J. Atkers, K. Guo, G.M. Fischer, E. Daltrozzo, A. Zumbusch, and S. Achilefu
Long Fluorescence Lifetime Molecular Probes Based on Near Infrared Pyrrolopyrrole Cyanine Fluorophores for In Vivo Imaging
Biophys. J. 97, L22 (2009) - G. M. Fischer, M. Isomäki-Krondahl, I. Göttker-Schnetmann, E. Daltrozzo, and A. Zumbusch
Pyrrolopyrrole Cyanine (PPCy) dyes: A new class of near-infrared dyes and fluorophores
Chem. Eur. J. 15, 4857 (2009)